2017 top 5 medical device companies

all rights belong to Monique Ellis (ProClinical.eu)

Medtronic – 2016 revenue: $29bn – The leading medical device company in the world, Medtronic, enjoyed a staggering 42% growth in revenue compared with 2015 figures ($20.3 billion). The medical device giant operates in over 140 countries and employs more than 100,000 people that work across its principal units: cardiovascular, diabetes, spinal and biologics, neuromodulation, surgery and cardiac rhythm disease. Much of 2016 growth can be attributed to the completion of a very successful acquisition of medtech company Covidien.

Johnson & Johnson – 2016 revenue: $25.1bn – The second biggest medical device company on the list is American biopharmaceutical, consumer goods and medical device giant Johnson & Johnson, which has been a well-known household name across the globe for several decades. Their ranking on this list is based on the revenue from the company’s medical device subsidiaries that include Ethicon, Acclarent and DePuy Synthes. The group develop and manufacture products in various therapy areas: orthopaedic, cardiovascular, diabetes, vision care and surgery. The company saw a 2.6% increase in revenue in 2016 and intends to drive further growth in 2017 through greater innovation, portfolio management and by expanding into emerging markets.

GE Healthcare – 2016 revenue: $18.2bn – In the top three medical device companies in the world, General Electric is another multinational conglomerate that has a thriving healthcare segment, commonly known as GE Healthcare. The company produces medical devices like x-rays, ultrasound machines, incubators and CT image machines. It also develops devices that aid research and drug innovation and biopharmaceutical manufacturing. In 2016, the company experienced healthy 17.3% margin and in 2017, it aims to grow by expanding further into emerging markets and China. Recently, GE Healthcare has committed $300million under their initiative, Sustainable Healthcare Solutions, which aims to bring ‘disruptive technologies’ to these emerging markets where healthcare is less accessible.

Fresenius (Medical Care) – 2016 revenue: $18bn – German medical devices company Fresenius Medical Care specialises predominately in developing medical supplies to treat patients with renal (kidney) diseases, particularly to aid dialysis. The company attributes strong growth of 7% in 2016 to an increase in sales of dialysers and machines as well as positive price and volume effects. It also grew its workforce from 104,033 in 2015 to 109,319 in 2016, a 5% increase. Fresenius Medical Care  intends to boost annual revenues to $28 billion by 2020.

Philips (Healthcare) – 2016 revenue: $16bn – 5th on a list of top medical device companies, Philips is a global conglomerate company that is the largest manufacturer of lighting in the world. Their healthcare segment is also hugely successful, developing medical devices in a number of therapy areas including anaesthesia, oncology and cardiology. The company experienced a 3% growth in sales in 2016 in part thanks to a serious of successful growth initiatives, including the acquisition of PathXL in June 2016 and the integration of Volcano back in 2015.

have a look at ProClinical Life Sciences Recruitment Blog to see the full top 10 list!


10 Career Lessons

all rights belong to Bernard Marr, the author of this post

Life is short. Here’s the thing: Life is too short to put up with a job you hate, a boss who demeans you, or a company with no soul. Many people convince themselves that they can put up with a job or career situation that makes them unhappy because they need the income, because they don’t know if they can find another job, or for some other reason. But the truth is none of us knows how long we have on this earth, and spending too much of it in a bad situation will only make you miserable and regretful. If you’re in this situation, take a step today — no matter how small — toward a better situation.

Social networks matter. You might think that networking events are dull, that it’s boring to chat with coworkers around the watercooler, or that you’re simply a born introvert, but study after study confirms that social networks are vital to our success. In fact, the most successful people tend to have the broadest and most diverse social networks. The more time and effort you put into nurturing your social networks, the more successful you are likely to be.

Sacrificing your health for success or wealth isn’t worth it. Many driven, successful people have a hard time creating work/life balance and can end up burning out or developing serious health problems from stress and overwork. The truth is, it’s much easier to stay healthy than to heal from a problem or disease — and no amount of success or money can replace your health. Don’t take your health for granted and take steps to mitigate stress that could cause problems later.

None of the best moments of your life will take place looking at a screen. In our connected world, it’s tempting to let all the little screens we have access to dictate our lives. But you’ll never reach the end of your life wishing you’d spent more time checking email on your phone. Disconnect regularly and experience real life.

Never stop learning. With the rate at which technologies are changing today, if you decide that you are “done” learning, you will be left behind within a matter of years, if not sooner. The idea that you can’t teach an old dog new tricks is blatantly false, and you will never wake up and regret having invested in your mind by learning something new.

Diversify. Hand in hand with learning, if you stick to only doing what you know, or what you are good at, you may quickly find that you’re only good at one thing. We need to be agile, nimble, and interested in many different things. Otherwise, you could get stuck in a job or career you don’t love, or that goes with the times. Think of the taxi driver threatened by Uber or the customer service person replaced by a chatbot.

You can go fast alone, but you can go farther together. In other words, teamwork makes the dream work. Many people claim they don’t like to work in teams, but the ability to work well in teams is vital if you want to succeed. The idea of the solo auteur is a myth; every big idea needs a team to make it happen.

Worrying doesn’t achieve anything. The antidote to fear and anxiety is action and hustle. If you’re wasting time because you’re afraid to pursue an idea, speak up, or are worried what others will think of you, you won’t achieve your goals. If you push through the worry and the fear, however, and take action, you’ll almost always find that you were worried about nothing.

Failure is not an end. If you give up when you fail, you’ll never learn anything. Instead, look at failure as an opportunity, as the beginning of a new journey. If you do, you’re much more likely to try again and succeed at something else.

Happiness is a journey, not a destination. So many people put off their happiness; they think, “I’ll be happy when I get that job, when I lose that weight, when I’m in a relationship, when I’m out of a relationship…” and so on. But we can choose to be happy. Happiness is a habit and a choice. No matter what your situation, if you can approach it with an attitude of happiness, you will be more successful.

3-D scanning with water

source: this website

A global team of computer scientists and engineers have developed an innovative technique for 3D shape reconstruction. This new approach to 3D shape acquisition is based on the well-known fluid displacement discovery by Archimedes and turns modeling surface reconstruction into a volumetric problem. Most notably, their method accurately reconstructs even hidden parts of an object that typical 3D laser scanners are not able to capture.

3D scannerTraditional 3D shape acquisition or reconstruction methods are based on optical devices, most commonly, laser scanners and cameras that successfully sample the visible shape surface. But this common approach tends to be noisy and incomplete. Most devices can only scan what is visible to them but hidden parts of an object remain inaccessible to the scanner’s line of sight. For instance, a typical laser scanner cannot accurately capture the belly or underside of an elephant statue, which is hidden from its line of sight.

The team’s dip transform to reconstruct complex 3D shapes utilizes liquid, computing the volume of a 3D object versus its surface. By following this method, a more complete acquisition of an object, including hidden details, can be reconstructed in 3D. Liquid has no line of sight; it can penetrate cavities and hidden parts, and it treats transparent and glossy materials identically to opaque materials, thus bypassing the visibility and optical limitations of optical and laser-based scanning devices.

water 3D scanningThe research, “Dip Transform for 3D Shape Reconstruction“, is authored by a team from Tel-Aviv University, Shandong University, Ben-Gurion University and University of British Columbia. They implemented a low-cost 3D dipping apparatus: objects in the water tank were dipped via a robotic arm. By dipping an object in the liquid along an axis, they were able to measure the displacement of the liquid volume and form that into a series of thin volume slices of the shape. By repeatedly dipping the object in the water at various angles, the researchers were able to capture the geometry of the given object, including the parts that would have normally been hidden by a laser or optical 3D scanner.

The team’s dip transform technique is related to computed tomography, an imaging method that uses optical systems for accurate scanning or to produce detailed pictures. However, the challenge with this more traditional method is that tomography-based devices are bulky and expensive and can only be used in a safe, customized environment. The team’s approach is both safe and inexpensive, and a much more appealing alternative for generating a complete shape at a low-computational cost using an innovative data collection method.

In the study, they demonstrated the new technique on 3D shapes with a range of complexity, including a hand balled up into a fist, a mother-child hugging and a DNA double helix. Their results show that the dip reconstructions are nearly as accurate as the original 3D model, paving the way to a new world of non-optical 3D shape acquisition techniques.

what’s up, Handle?


Handle is a research robot that stands 6.5 ft tall (about 2 meters), travels at 9 mph (about 14.5 kmh) and jumps 4​ ​feet vertically (about 1.2 m). ​It uses electric power to operate both electric and hydraulic actuators, with a range of about 15 miles (about 24 km) on one battery charge. ​​​Handle uses many of the same dynamics, balance and mobile manipulation principles​ found in the quadruped and biped robots built by Boston Dynamics, but with only about 10 actuated joints, it is significantly less complex. Wheels are efficient on flat surfaces while legs can go almost anywhere: by combining wheels and legs Handle can have the best of both worlds.

Faster, noninvasive method to determine the severity of a heart failure

source: this website

tueMethods currently employed to determine the severity of a heart failure are very limited. Researchers at Eindhoven University of Technology and the Catharina Hospital in Eindhoven have therefore developed a method that is very quick, non-invasive, cost-effective and can be performed at the hospital bedside. Moreover, this method appears to have a predictive value for whether or not a double pacemaker will be successful. Researchers Ingeborg Herold and Salvatore Saporito received their doctorates last month for their study.

Heart failure – when the heart is no longer able to pump enough blood through the body – is a very common problem. To get the right treatment, it is important to measure how well the heart is still able to do its job. There are currently various methods for doing this, but all have their limitations. Sensors often need to be placed in the large arteries, via the shoulder or neck, and that is quite an invasive procedure. MRI is a possibility, but not for patients that are seriously ill. Patients that are short of breath nearly always undergo blood analysis, a method that examines the concentration of a particular protein in the blood and provides a very good, patient-friendly indicator, but it takes several hours before the outcome is known.


The Eindhoven researchers have developed a patient-friendly method that uses an echo scanner, which is known mainly for echoes performed during pregnancy, to determine the severity of heart failure. To do this, they measure the time it takes for the blood to travel from the heart’s right ventricle through the lungs to the left ventricle, which is responsible for pumping oxygenated blood through the body. In order to measure this pulmonary transit time (PTT), they inject harmless microbubbles that can be seen clearly by the echo scanner. They then look at the heart and see how long it takes for the bubbles to get from the right to the left ventricle.

animatedpacemakerIt may seem simple enough but there was a significant scientific challenge in calculating an unequivocal PTT for the observed microbubbles that get dispersed in the blood flow. But once that had been solved, they compared the transit time with a number of existing indicators, developing a similar method on the basis of MRI. Comparisons revealed that the PTT measured with the echo scanner provides an excellent indicator for the severity of a heart failure. A healthy heart pumps the blood quickly through the lungs. The longer the PTT, the less well the heart performs. They examined subjects whose heart muscle no longer contracted well, which is the most common type of heart failure. Before the method can be used, there is still work to be done. For example, if it is to be both practical and fast, the analysis will have to be automated.

Ingeborg Herold gained her doctorate on Thursday 17 November for her thesis “Assessment of cardiopulmonary function by contrast enhanced echocardiography” while Salvatore Saporito received his PhD the same day for his thesis “Cardiovascular MRI quantifications in heart failure“.